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A new development in the Madeleine McCann case is expected within the next few days, Sky News has learnt.

Madeleine now missing for 109 days. Crime correspondent Martin Brunt understands detectives may want to question a man who was in the Algarve holiday resort of Praia da Luz on the night the four-year-old disappeared.

He believes the development could tie in with alleged inconsistencies in the statements of those who were with Gerry and Kate McCann on May 3.

It follows reports in the local Portuguese media that police may be about to arrest a second British suspect.

Brunt says increased activity surrounding the case rings true with recent suggestions from Portuguese police that developments are likely within the next few weeks.

Mistaken identity: Sjanneke HofstedePolice leave has been cancelled and officers have been granted a number of new search warrants which they are expected to execute within the next 48 hours.

"Certainly there is renewed activity in the case," Brunt said.

"More searches are about to begin and there could be a new suspect. It all suggests there is a new impetus to the investigation."

The latest developments in the case come as investigators wait on DNA test results on specs of blood found inside the McCanns's Algarve holiday home.

Madeleine has now been missing for 109 days. She vanished from the flat as her parents dined nearby.

Meanwhile, Belgian police have ruled out a possible sighting of Madeleine at a cafe last month.

The four-year-old in question, Sjanneke Hofstede, was spotted at the cafe with her father.

http://news.sky.com/skynews/article/0,,91210-1280490,00.html

The Portuguese detective leading the hunt for Madeleine McCann says he has a "positive feeling" about the inquiry.

Madeleine: missing for 110 daysChief Inspector Olegario Sousa also indicated that a clearer picture may be emerging of what happened to the child on the night she vanished.

Mr Sousa was speaking as detectives awaited the results of tests on specks of blood found in the Praia da Luz holiday flat from where the four-year-old disappeared on May 3.

The spokesman for Portugal's investigative Policia Judiciaria said: "We have already said that all the lines are still open.

"...We haven't enough information to make the picture of what happened that night. But we are with a positive feeling on this."

Pressed on whether a clearer picture of what had happened to Madeleine was emerging, he said: "Yes, you might say so.

"But we are not with all the information at the moment - we are putting together information."

Mr Sousa's latest comments come amid renewed police activity in the Algarve resort town.

All police leave has been cancelled and officers have been granted a number of new search warrants which they are expected to execute over the next few days.

It is now 110 days since Madeleine disappeared from her family's apartment as her parents, Kate and Gerry, dined nearby with friends.

Anglo-Portuguese ex-pat Robert Murat, 33, is still the only official suspect in the case.

http://news.sky.com/skynews/article/0,,91210-1280780,00.html